Cannabis has historically been stigmatized due to its effects; however, it is now receiving growing acknowledgment for its potential in various medical fields. In recent years, research into the therapeutic properties of cannabis has notably increased, especially regarding its benefits for neurological conditions.
In addition to its well-known uses for stress relief, alleviating depression, and enhancing sleep, cannabis shows potential in addressing a range of neurological disorders. This article explores five such conditions and investigates how a Weedsy Canada weed pen or cannabis contributes to their therapeutic applications.
Table of Contents
Key Takeaways:
- Certain cannabinoids and terpenes demonstrate distinct effects on various neurological disorders.
- Linalool, myrcene, and limonene possess anti-convulsant properties.
- Equal proportions of THC and CBD, alongside other cannabis compounds, may be beneficial in cancer treatment.
A Natural Approach to Managing Neurological Disorders
Addressing the complexities of conditions such as Alzheimer’s disease (AD), brain tumors, Parkinson’s disease (PD), intractable epilepsy, and chronic traumatic encephalopathy (CTE) or traumatic brain injury (TBI) varies based on individual patient needs and the severity of their conditions.
Cannabis is a Viable Treatment Option
Epilepsy
The endocannabinoid system plays a crucial role in influencing the seizure threshold. THC, in particular, can effectively halt seizures, unlike phenobarbital and diphenylhydantoin. Animal studies indicate acute spikes in endocannabinoid production and a sustained increase in CB1 production over time. Researchers have noted the anti-convulsant effects of cannabinoids even at non-sedative levels.
THC, THCA, and linalool, a terpenoid found in cannabis, have been subjects of scientific investigation. The dialogue surrounding THCA is intricate, with discussions about its CB1 activity versus its spontaneous conversion to THC.
Recent findings also illuminate the anti-convulsant properties of cannabidiolic acid (CBDA), suggesting serotonergic effects. CBDA exhibits a significantly higher affinity for the 5-HT1A receptor compared to CBD.
If you are interested in exploring cannabis vape pens to aid your condition, seek products containing THC, CBD, THCA, or Linalool.
OneStop – THC Distillate Disposable Vape pen Skittlez features linalool as a primary terpene with THC levels ranging from 16 to 21%.
Brain Tumours
Numerous studies have examined the use of cannabis in patients diagnosed with brain tumors. A study published in the British Journal of Cancer in 2006 found that administering THC directly into tumors in patients with glioblastoma multiforme (GBM) marginally extended their lives beyond expectations in nine cases.
A case report from the Journal of Child’s Nervous System documented complete regression of residual tumors in two children with pilocytic astrocytomas after smoking cannabis.
THCA, acting as a peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, shows greater efficacy than CBDA, CBD, or THC in potential impact. PPARs function as ligand-binding transcription factors, promising to target cancer cells while leaving normal cells unharmed. The synergistic effects of THCA with other cytotoxic agents underscore its potential in cancer treatment.
Equal concentrations of THC and CBD, when combined with THCA, CBDA, and cytotoxic terpenoids like limonene, hold significant promise in cancer treatment, as suggested by a study in the Planta Medicine Journal. Disposable cannabis pens can incorporate these cannabinoids and terpenes in a single cartridge.
Parkinson’s Disease
An observational study revealed that 22 out of 28 patients could tolerate smoked cannabis, presumably THC-predominant. The study also highlighted acute benefits, including improvements in tremor, rigidity, and bradykinesia among participants.
In Parkinson’s disease, the loss of cells in the substantia nigra often leads to widespread pathology over time. Changes in tau proteins, which support the cytoskeleton and facilitate axonal transport in neurons, result in neurofibrillary tangles.
Nabiximols, a cannabis-based oral spray, substantially reduced tangles when researchers administered it to parkin-null mice expressing human tau. This treatment improved dopamine metabolism and glial function and lowered oxidative stress levels.
THC vape pens like Weedsy Canada OneStop THC Pens can be an excellent option if you seek to improve tremors.
Alzheimer’s Disease
Alzheimer’s disease (AD) involves the formation of senile plaques from β-amyloid (Aβ) proteins, which occur when enzymes cleave a precursor protein (APP). Additionally, neurofibrillary tangles arise from tau proteins that accumulate excessive phosphate groups. Sometimes, these tangles form before the β-amyloid plaques. Once these processes commence, the progression of the disease is irreversible.
CBD acts as a protective antioxidant for the brain, safely interacting with NMDA receptors. It performs several functions to combat Alzheimer’s disease: it halts the formation of Aβ plaques, diminishes harmful ROS production, and prevents damage to fats in PC12 cells exposed to Aβ. CBD also obstructs tau proteins from acquiring excessive phosphate groups on PC12 neurons affected by Aβ.
In a study, patients received THC-predominant (2.5–30 mg/dose), CBD-predominant, and THCA, primarily administered through tinctures and confections. Patients reported reduced dependency on neuroleptic drugs, alleviated agitation, improved appetite, managed aggression, enhanced sleep quality, elevated mood, decreased reliance on nursing care, mitigated self-mutilation tendencies, and controlled pain.
Cannabis components demonstrate the potential to address various symptoms associated with this complex disorder:
- Agitation may find relief with THC, CBD, and linalool.
- Psychosis symptoms may benefit from CBD.
- THC and linalool may alleviate insomnia and restlessness.
- THC is indicated for anorexia, while THC, CBD, and linalool may help with aggression.
- THC, limonene, and CBD could potentially assist in managing depression.
- THC and CBD are known for pain-relieving properties.
- Alpha-pinene, in addition to THC, is associated with memory enhancement.
- CBD and THC are linked to neuroprotection, while THC, CBD, and THCA may contribute to reduced Aβ plaque formation.
Traumatic Brain Injury / Chronic Traumatic Encephalopathy
Cannabis, particularly chemovars combining THC and CBD, can alleviate symptoms associated with CTE, including headache, nausea, insomnia, dizziness, agitation, substance abuse, and psychotic symptoms.
A 2019 study revealed that varying concentrations of THC and CBD contribute to relieving stress, agitation, depression, and anxiety—common emotional manifestations in chronic traumatic encephalopathy cases. Cannabinoids help mitigate glutamate excitotoxicity, a process leading to nerve cell damage following traumatic brain injury.
Want to Use cannabis for Your Current Condition?
Engaging in cannabis use is a common approach to harness its benefits. If you’re looking to avoid the potential health risks associated with traditional methods, cannabis vapes offer a viable alternative.
Weed vape pens are equipped with a heating chamber or element that transforms the flower or concentrate into vapor. Online cannabis stores provide numerous options to help you find the best vape pen for your needs. You can select based on the pen type, including disposable vape pens, and whether you prefer Sativa-dominant or Indica-dominant cartridges with high THC or the specific concentrate it utilizes.
Weed Vape Pens Treat Your Condition
Neurological treatment for the conditions discussed in this article requires significant progress. However, emerging methods like utilizing cannabis, including through a cannabis pen, in treatment protocols show promise. Research studies and anecdotal evidence suggest that cannabis, with its varying levels of THC, CBD, and other compounds, can interact with the ECS to help manage symptoms of these conditions.
Frequently Asked Questions
Can a dab pen provide the same experience as a vape pen?
A dab pen and a vape pen both vaporize cannabis concentrates but differ in intensity and usage. Dab pens are designed for solid concentrates like wax, delivering a more intense effect. Vape pens utilize liquid concentrates, providing a milder, more controlled experience.
Are THC pens affordable?
The average cost of a cannabis pen is approximately $50. You’ll find options as economical as $20 and others reaching $200 or more. The price variation depends on battery life and the range of features available.
Can my current medication interact with the active ingredient in my cannabis vape?
This depends on your prescription drug. If you take anti-depressants while managing Parkinson’s disease, cannabis might lead to an initial surplus of serotonin, intensifying your body’s reliance on these substances, which could worsen depression and anxiety over time. It’s advisable to consult your doctor before considering adding cannabis to your current medication regimen.
Are cannabis pens the best alternative when treating health issues with cannabis?
Weed pens provide a cleaner method to use cannabis without the smoke from combustion, making them a popular choice for individuals seeking a less harmful and more discreet option to manage health issues like pain and anxiety.
Nonetheless, whether cannabis pens are the best choice depends on the individual using them. Given that we are still learning about their long-term effects, it is crucial for anyone contemplating their use for health reasons to discuss it with a doctor first. This ensures they are selecting the most suitable method for their health needs.
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